There are areas around the Costa that have been laid by local councils and builders. The issue with these areas is that the granules are being laid too thinly and quite possibly with the incorrect ratio of Polymer to granules thus causing the surfaces to break up. We carefully measure the quantities of polymer when mixing to ensure that the ratio is correct to allow the granules to stick together permanently. We also lay to a minimum depth of 15mm to ensure that the surface remains firm and stands up to normal wear and tear.
No dose adjustment of Lotrel is required in patients with creatinine more information.